Lebanon Red Cross says the explosion at Beirut port killed more than 135 people and injured over 5,000.
The blast also devastated an entire neighbourhoods in the city.
“Until now over 5,000 people have been injured and over 135 have lost their lives. Our teams are still conducting search and rescue operations in the surrounding areas,” a statement said.
Meanwhile, the UN Secretary-General Anténio Guterres commiserated with the people and government of Lebanon over the explosion.
The UN chief’s reaction came in a statement by his deputy spokesman, Mr Farhan Haq.
“The Secretary-General expresses his deepest condolences to the families of the victims.
“He also commiserates with the people and government of Lebanon following the horrific explosions in Beirut.
“He wishes a speedy recovery to the injured, including several United Nations personnel working in Lebanon.
“The United Nations remains committed to supporting Lebanon at this difficult time, and is actively assisting in the response to this incident,” Haq said.
US. Ambassador to Lebanon, Dorothy Shea, also reacted to the incident with a condolence message.
She also described the explosion in Lebanon as horrific.
“Having witnessed the horrific explosions at the port this evening, our heartfelt sympathies go out to the victims and their families.
“We mourn each loss from this terrible tragedy alongside the Lebanese people,” the embassy quoted her as saying in a tweet.
Authorities say the blast occurred when a fire at a warehouse on the city’s waterfront ignited a cache of explosive ammonium nitrate
The warehouse sheltered the chemicals for more than six years at the site.